Ardo Illaste edited figures/fit_linescan/caption.md  about 10 years ago

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\label{fig:fig2}  Fitting a linescan image. **A** Each time trace in the raw fluorescence signal is fitted and a denoised image is obtained. **B** The denoised image is a sum of fitted events (**C**) and baseline (**D**). ΔF/F0 image (**E**) is obtained by dividing the event image (**C**) with the baseline (**D**). Because the fitted baseline is a function of time, the F_0 ΔF/F0 image is automatically corrected for temporal changes in background flourescence (e.g., bleaching). **F** The residual signal obtained when subtracting the fitted image from raw data. **G** Residual values are normally distributed.\label{fig:fig1}  Fitting function. **A**: Fitting function for transients given by eq 1. **B** Result of fitting raw fluorescence data with the combined fitting function. **C** Raw signal is the sum of the fit, noise (W) and residual (R). **D** The fit is a superposition of the baseline and pixel events.