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Jennifer Shelton edited introduction.tex
over 8 years ago
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\subsection{Existing tools}
Many bioinformatics tools already address FASTA format inconsistencies. However many tools either halt and exit with an error (e.g.
BioPerl) BioPerl \cite{bioperl}, \cite{bioperl2}, \cite{bioperl3}) or can produce can reformatted output FASTA but cannot determine if there is a formatting issue to begin with (e.g. EMBOSS Seqret \cite{PMID:10827456}).
The BioPerl module \verb|DB::Fasta| will halt if a FASTA is inconsistently wrapped or if a line of sequence is too long (as in an unwrapped genome FASTA). This has the disadvantage of requiring intervention to wrap and restart analysis.
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