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SAXS and SANS are also popular methods for the size measurement of macromolecules. While they can be used with higher particle concentrations than DLS ($\sim$1-100~mg/ml) and are applicable to a large MW range from few kDa to hundreds of MDa, they have low resolution, and structural information can only be obtained through complex model building.\cite{Pecora_1985} Similar to DLS, SAXS and SANS measure scattering from unlabelled molecules which simplifies sample preparation but makes the results susceptible to artefacts arising from dust and other contamination in the sample solution, and makes these techniques impossible to be used with scattering media, such as tissue.  The measurement time interval of 5~$\mu$s used in these experiments is ideal for measuring the rotational correlation times of these proteins drugs  with this Ru dye at low viscosities. However, with the long lifetime of the dye, long pixel dwell times are needed, making scanning-based data acquisition slow. We have recently developed wide-field lifetime imaging approaches \cite{Hirvonen2014_ol, Hirvonen2015_njp} that are ideally suited for measuring lifetimes at this time scale, and could image several wells containing different drugs and/or different viscosity solutions simultaneously. These methods might benefit the size measurement of similar or higher MW drugs, and enable imaging these drugs \textit{in vitro}.