Christopher Medway edited Introduction.tex  over 8 years ago

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\section{Introduction}  \textit{Yersinia} is a genus of gram-negative enterobacteriaceae. Of the eleven characterised species of Yersinia, three have been particularly well studied due to their pathogenicity to humans; \textit{Y.pestis}, \textit{Y.pseudotuberculosis} and \textit{Y.enterocolitica}. \textit{Y.pestis} is highly pathogeneic, resulting in a systemic disease 'plague' the may affect the lungs, lymph nodes and blood vessels. Conversly \textit{Y.pseudotuberculosis} and \textit{Y.enterocolitica} are entropathogens, primarily affecting the gastrointestinal system where they can cause local inflammation and diarrhea. \textit{Y.entrocolitica} strains are particularly diverse, containing a spectrum of non-pathogenic ('1A'), (1A),  mildly-pathogenic ('2'-'5') (2-5)  and pathogenic ('1B') (1B)  biovars.