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\begin{tabular}{l c c}  Target & Best $p$-value & Sig. Queries \\   \hline  CathG & 4.23e-06 & 5.2\%  ER$\alpha$ 1\%  ER$\alpha$ & 0.0505 & 0.0\% 0\%  ER$\alpha$ agonist & 0.0106 & 0\%  ER$\beta$ & 0.0328 & 3.9\% 0\%  FAK & 0.000289 & 7.3\% 4\%  FXIa & 0.387 & 0.0\% 0\%  HIVrt & 0.000951 & 12.7\% 5\%  HSP90 & 0.000755 & 5.6\% 2\%  PKA & 1.14e-23 & 93.3\% 80\%  Rho & 8.41e-15 & 94.1\% 80\%  \end{tabular}   \caption{\label{pvaltable} Significance of the best shape constraint queries (include queries not on the pareto-optimal frontier)  and the percentage of all evaluated queries with a Bonferroni-corrected p-value $p$-value  below 0.05.} 0.01.}  \end{table}