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Campari \cite{Vitalis_2009} conducts flexible Monte Carlo sampling of biopolymers in internal coordinate space, with built-in analysis routines to estimate structural properties and support for replica exchange and Wang-Landau sampling.  GALAMOST (GPU accelerated large-scale molecular simulation toolkit) \cite{Zhu_2013} uses GPU computing to perform traditional molecular dynamics with a special focus on polymeric systems at mesoscopic scales.  Gromacs \cite{Pronk_2013} is a complete and well-established package for molecular dynamics simulations that provides high performance on both CPUs and GPUs. It can be used for free energy and QM/MM calculations.  Iphigenie \cite{Lorenzen_2012} is a molecular mechanics program that features polarizable force fields, the HADES reaction field, and QM/(P)MM hybrid simulations.