deletions | additions       diff --git a/LigBuilder_v2_0_is_a__.tex b/LigBuilder_v2_0_is_a__.tex  index c63bda4..1d917df 100644  --- a/LigBuilder_v2_0_is_a__.tex  +++ b/LigBuilder_v2_0_is_a__.tex 
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LigBuilder v2.0 is a structure-based de novo drug design and optimization program. Ligand molecules within the binding pocket are built based on the three-dimensional structure of the target protein and subsequently screened. Main properties of LigBuilder v2.0 include: detect and analyze the ligand-binding site of the target protein with Cavity, explore design, optimize lead, link fragment, mimic design, estimate binding-affinity, filter ligand, recommend ligand, analyze synthesis, substructure search, and cluster molecule with Build, Fragment Database, Forbidden Database, Toxicity Database, and Synthesis Database \cite{Wang_2000}. \cite{Wang_2000}\cite{Yuan_2011}.