this is for holding javascript data
Niranjana Nagarajan edited abstract.md
over 10 years ago
Commit id: 2da464ca0da0ea2b07080e15a76ec6d3ad2bdbbe
deletions | additions
diff --git a/abstract.md b/abstract.md
index 68fd296..9eacffb 100644
--- a/abstract.md
+++ b/abstract.md
...
Scott Fay,
Kyle Taylor
Molecular manipulation of the genetic pathways of living organisms has the potential to change lives in many ways, such as providing more effective anti-malarial
medicine medicine, insulin, or useful bio-materials like spider silk grown from bacteria.
Insulin, [Insulin, previously extracted from animals, was expensive and scarce until the gene was inserted into bacteria and breakthrough human insulin became widely
available. available.] The field of synthetic biology is still in its infancy and much remains to be learned about how to most efficiently stitch
these [these] genetic parts together. Generally, researchers combine promoters and genes in order to produce a desired protein. However, the amount of protein present in the cell is more than just a function of its promoter. Protein levels are typically measured by RNA levels, as RNA polymerase recognizes and binds promoters, but in fact RNA levels are often poor predictors of protein levels. Factors such as protein degradation rate or translation initiation (the topic under consideration here) are important to consider as well.
We present ribosome binding and translation initiation candidate DNA parts derived from publicly available data and look for correlations to protein levels, focusing on the widely studied plants Oryza sativa and Arabidopsis thaliana. The working group is open to the public and we have had over 50 individuals participate to date. The group meets every other week for 3 hours typically starting with a short presentation related to the session’s agenda followed by hands-on data work. We hope our experience will serve as a model for future community projects that serve the dual purpose of educating curious members of the public while also generating useful scientific results. We aim to develop and experimentally validate our consensus sequences for publication with hopes that our work will be useful for researchers in plant synthetic biology, such as the Glowing Plant Project initiated at the BioCurious community laboratory in Sunnyvale, California.