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Bishesh Khanal edited subsection_Modeling_and_Prediction_of__.tex
about 8 years ago
Commit id: c2a5d826fc2d4fd120cd4e31142ffadb1eab5154
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% Raj A, LoCastro E, Kuceyeski A, Tosun D, Relkin N, Weiner M, for the Alzheimer’s Disease Neuroimaging Initiative (ADNI). Network Diffusion Model of Progression Predicts Longitudinal Patterns of Atrophy and Metabolism in Alzheimer's Disease. Cell Rep. 2015 Jan 14; PubMed.
And the website (in comments)
%% http://www.alzforum.org/news/research-news/computer-model-predicts-how-pathology-spreads-alzheimers-disease
Two-fold motivation of modeling and simulating AD
trajectories: trajectories:\\
First:\\
The biomarkers evolution show that the drugs will target the A$\beta$ or tau proteins.
The effect should be seen in the structural MRIs in atrophy before looking at the cognitive functions.