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Alois Alzheimer in 1907 reported\cite{Alzheimer1907,stelzmann1995}  a study of one of his patients with "an unusual illness of the cerebral cortex". cortex" \cite{Alzheimer1907,stelzmann1995}.  Alzheimer details the symptoms of his patient suggesting that they were so unusual that the patient could not be classified as having one of the recognized illnesses.  "\textit{The first symptom the 51-year-old woman showed was the idea that she was jealous of her husband.