David Andrew Eccles edited This_12_SNP_comparison_set__.tex  almost 9 years ago

Commit id: f1f14c658efa35417eb93a2b131d8f860e57ad6f

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This 12-SNP comparison set had an AUC of 0.73 when tested with 1963  T1D cases and 1458 NBS controls. Setting the false positive rate to  5\% (cutoff Q value 0.933) produced a true positive rate of 18\%,  while setting the true positive rate to 85\% (cutoff Q value 0.895)  produced a false positive rate of 53\%. The position on the curve  nearest to a true positive rate of 100\% and a false positive rate of  0\% was when the cutoff Q value was set at 0.910, with a true positive  rate of 65\%, and a false positive rate of 35\%. These results  indicate that the signature SNP set discovered in the present study is  considerably more informative than a set of T1D-associated SNPs found  in other genome-wide association studies. BLANK TEXT