David Andrew Eccles edited section_Method_and_Results_label__.tex  almost 9 years ago

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sample was derived from.  The problem of discovering associated features that are not present in  the more general case is known as overfitting \cite[see][Chapter \citep[see][Chapter  14, pp. 661-663]{russell2003}. In the conventional GWAS context,  overfitting produces false positive associations, where an association  with a particular genotype does not extend to the general population. 

indicate that the signature SNP set discovered in the present study is  considerably more informative than a set of T1D-associated SNPs found  in other genome-wide association studies.