<p><u>Mass&nbsp;spectrometry biosensor:</u><br></p><div>Mass spectrometry biosensors (MS) use technique
measure the changing of mass ratio or vicissitude of particles or ionizing chemical
when the molecules interaction with &nbsp;&nbsp;element of composition of the film surface
with add the mass on surface. The deviation of mass change will convert to the
signal analysis. The principle of characteristics of individual of molecules or
composition to ions and let those ions moving in the electric field or magnetic
field. The technique base on three principle ionized, mass analyzer, and
detector, Ionized to cations by losing electron in structure. The second part
to use mass analyzer with separated mass and charge of element or composition.
The last part is the detector which registers the number of value (m/z)[<cite class="ltx_cite" data-bib-text="@article{1986,
	doi = {10.1016/0265-928x(86)85019-2},
	url = {http://dx.doi.org/10.1016/0265-928x(86)85019-2},
	year = 1986,
	month = {jan},
	publisher = {Elsevier {BV}},
	volume = {2},
	number = {1},
	pages = {63--64},
	title = {Workshop on mass spectrometry in biotechnological process analysis and control},
	journal = {Biosensors}
}" data-bib-key="1986" contenteditable="false"><a href="#1986">1986</a></cite>]. This technique
increase precisely and quantify and analysis the thousands of proteins complex
structure [<cite class="ltx_cite" data-bib-text="@article{Feng_2008,
	doi = {10.1002/mas.20182},
	url = {http://dx.doi.org/10.1002/mas.20182},
	year = 2008,
	month = {nov},
	publisher = {Wiley-Blackwell},
	volume = {27},
	number = {6},
	pages = {635--660},
	author = {Xiaojun Feng and Xin Liu and Qingming Luo and Bi-Feng Liu},
	title = {Mass spectrometry in systems biology: An overview},
	journal = {Mass Spectrom. Rev.}
}" data-bib-key="Feng_2008" contenteditable="false"><a href="#Feng_2008">Feng 2008</a></cite>][<cite class="ltx_cite" data-bib-text="@article{Gstaiger_2009,
	doi = {10.1038/nrg2633},
	url = {http://dx.doi.org/10.1038/nrg2633},
	year = 2009,
	month = {sep},
	publisher = {Nature Publishing Group},
	volume = {10},
	number = {9},
	pages = {617--627},
	author = {Matthias Gstaiger and Ruedi Aebersold},
	title = {Applying mass spectrometry-based proteomics to genetics,
genomics and network biology},
	journal = {Nat Rev Genet}
}" data-bib-key="Gstaiger_2009" contenteditable="false"><a href="#Gstaiger_2009">Gstaiger 2009</a></cite>]can be detection. The figure 6 shows the structure cantilever behavior
under interaction with molecule.<br></div><div><br></div>