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\begin{enumerate}  \item organic beings must be exposed during several generations to the new conditions of life to cause any appreciable amount of variation;  \item that when the organisation has once begun to vary, it generally continues to vary for many generations.  \end{enumerate} No case is on record of a variable being ceasing to be variable under cultivation. Our oldest cultivated plants, such as wheat, still often yield new varieties: our oldest domesticated animals are still capable of rapid improvement or modification.