this is for holding javascript data
Andrea Attili added M&M - Radiobiological - LEM.tex
over 9 years ago
Commit id: daef9eccec65e0f186ec416f339689bc9dfb754d
deletions | additions
diff --git a/M&M - Radiobiological - LEM.tex b/M&M - Radiobiological - LEM.tex
new file mode 100644
index 0000000..2e92273
--- /dev/null
+++ b/M&M - Radiobiological - LEM.tex
...
\subsection{Radiobiological Modeling}
\subsubsection{Local Effect Model Approach}
The Local Effect Model (LEM) \cite{Scholz_1996}, originally devised to predict the biological response of a cell irradiated with high LET (Linear Energy Transfer) charged particles, accounts for dose heterogeneities along ionizing particle tracks, and has been applied to the high-dose spots located near GNPs to determine the additional cell killing induced by the nanoparticles presence \cite{McMahon_2011}\cite{Lechtman_2013}. The LEM assumes that the cell response to inhomogeneous radiation dose on the micro-scale is similar to the response of the cell population as a whole to sparsely ionizing radiation.
