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Andrea Attili added Mat&Met - dose radial profile.tex
over 9 years ago
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\subsection{Materials and Methods}
\subsubsection{GNP dose enhancement radial profile simulations}
Knowledge of range and type of secondary particles, such as Auger electrons, photoelectrons or characteristic X-rays, and their variation with the primary photon energy is fundamental to develop a model delineating the GNP-photon interactions. Monte Calro simulations were carried out using the Geant4 simulation toolkit in which 2 nm GNPs placed at the center of a $10^3$ $\mu$m$^3$ cube of water were uniformly irradiated with different photon energies ranging from 50 keV to 15 MeV. Processes like Auger, photoelectric emission, and interaction of secondaries in nearby atoms were simulated to evaluate the ionization density following irradiation. Energetic cutoff of 10 eV were used for the production of secondary particles. In figure [tracce] are illustrated different track structures of ionizing events occurring at the surface and inside a 10 nm GNP following a 40 keV irradiation.
