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Veronica edited subsubsection_TCP_NTCP_models_One__.tex
almost 9 years ago
Commit id: b17a599b42e375803ac223ee9212445c4424c166
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diff --git a/subsubsection_TCP_NTCP_models_One__.tex b/subsubsection_TCP_NTCP_models_One__.tex
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--- a/subsubsection_TCP_NTCP_models_One__.tex
+++ b/subsubsection_TCP_NTCP_models_One__.tex
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The model used to quantify the TCP is based on Poisson distribution assumptions \cite{Munro_1961}, which take into account the tumor characteristics and organ architecture \cite{K_llman_1992}, and is also able to evaluate individual response to radiation and directly use the cell survival probability computed at the voxel level
\begin{equation}
\label{tcp} %\label{tcp}
\text{TCP} = \exp\left( -\text{d}v_i \sum_{i \in V} n_i \right)
\end{equation}
...
A phenomenological method to estimate the NTCP values for both uniform and nonuniform irradiation of many critical tissues is provided by the Lyman-Kutcher-Burman (LKB) model [Lyman 1985, Kutcher and Burman 1989, Mohan et al 1992, Deasy 2000, Li et al. 2003, and Luxton et al. 2008], which can be described by three equations:
\begin{eqnarray} \begin{align}
\label{ntcp}
\text{NTCP} &= \frac{1}{\sqrt{2\pi}} \int_{-\infty}^{t} e
\end{eqnarray} \\
t
\end{align}