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# Case Report  A 76-year-old male with a history of man presenting headche, nasal blockage and epistaxis was admitted in our hospital. A CT scan revealed  a small-cell neuroendocrine carcinoma growing mass  of soft tissue involving  the nasopharynx diagnosed from symptoms such as epistaxis etmmoidal cells, left maxillary, fontal left  and headache sphenoid sinus. Initial biopsy was not suggestive of neoplasic dissease. Complete excision through a lateral rhinotomy approach was performed. The postoperative histopathologic report was suggestive of sinonasal neuroendocrine carcinoma, which was confirmed by immunohistochemistry.  > -Febrero 2013:Diagnóstico de tumoración fosa nasal izquierda cT4N0M0 (AP carcinoma neuroendocrino de célula grande )Post-biopsia presenta:epilepsia + hematoma subdural + empiema frontal + cerebritis.  -Abril 2013: :Se realiza craneotomía bifrontal y exeresis de tumor nasoetomoidal infilitrante. Como complicación presenta status epiléptico.