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Alexei Drummond edited introduction.tex
over 8 years ago
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The fundamental conclusion of even the most rudimentary analysis is that amino acid sequence differences correlate well with morphological and paleontological considerations.
\end{quotation}
Despite this they went on to show evidence that rates of nucleotide substitution are not constant across vertebrates \cite{LangleyFitch1974}. Evidence for
or against the existence of a molecular clock (sometimes known as the `rate-constancy hypothesis')
played provided a key
role in support of the neutral theory of evolution and thus formed one of the battlegrounds between battleground on which neutralist and selectionist views of molecular evolution
were contested \cite{Kimura1987}.
Kimura \cite{Kimura1987} put it thus:
...