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\end{itemize}  Solving the problem  \begin{itemize}  \item Treat as absorbing boundary with drift, like Payam2.3. and solve diffusion equation (see page 3 of Payam's paper).  %  \item If we can make free energy change zero, then $\langle e^{-\beta W}\rangle = 1$. With dissipative process.  \end{itemize}