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Wen Jenny Shi edited Figure_reffigHIVHt_s.tex
over 9 years ago
Commit id: abfc18365021c55a565b20c66f20f45cc4f39b44
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The IVA strain consists of 8 segments: PB2 (2313 nucleotides (nts)), PB1 (2301 nts), PA (2303 nts), HA (1775 nts), NP (1396 nts), NA (1426 nts), M1/2 (1005 nts), and NS1/2 (869 nts). To reduce computational intensity, we examine each segment per replicate separately. Within each duplicate, we analyze the control and treatment groups over selected time points simultaneously. In particular, we choose five time points: 1, 3, 9, 12, and the end (13 and 18 for the Ruplicates I and II, respectively). Since the first three passages were shared across groups, there were total 8 time-samples, three of which were treated, for each biological replicate. Denote the 8 collection times as $t_1, t_2, t_3, t_4, t_5, t_{3D}, t_{4D}, t_{5D}$. The summary statistics are then formulated as
\begin{equation}
Ht(D_i) = \min\{ Ht(\pi_i^{t_1},\pi_i^{t_{5D}}), Ht(\pi_i^{t_2},\pi_i^{t_{5D}}), \}
\label{eq:HtFluDi}
\end{equation}
\begin{equation}
Ht(N_i) = \max\{ Ht(\pi_i^{t_1},\pi_i^{t_2}), Ht(\pi_i^{t_1},\pi_i^{t_j}), Ht(\pi_i^{t_2},\pi_i^{t_j}), \; j=3,4,5 \},
\label{eq:HtFluNi}