Rosamaria Cannavo edited Introduction.tex  about 9 years ago

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\section{Introduction}  \label{sec:Introduction}  \textit{General \textbf{\textit{General  introduction on the clock and cell cycle} cycle}}  The circadian clock and the cell cycle oscillators represent two cellular processes having a period in the range of one day.   At the single-cell level, the circadian rhythm is carried out by a network of transcriptional and translational feedback loops that drive rhythmic expression of genes with a period of about 24 hours. (ref) This cell autonomous rhythm is self-sustained (ref) and is considered to temporally orchestrate many important cell physiological processes such as metabolism (ref,ref), redox balance (ref) and chromatin landscapes/conformation (ref), {find other ph. Processes}. 

\textit{Observation \textbf{\textit{Observation  of interaction between the two cycles in different cells} cells}}  \textit{Amplyfing (work in progress)} 

\textit{Introduction \textbf{}\textit{Introduction  on model - \textbf{JON, {JON,  WHERE DO YOU WANT TO PLACE THIS SUBCHAPTER?} } \textit{}Interest \textbf{\textit{}Interest  of this topic topic}  Amplyfing \textit{Amplyfing  (work in progress) progress)}  A deeper understanding of how the two biological systems interact is currently of great interest, notably to better understand the role of circadian clocks in proliferating tissues such as the epidermis, immune or stem cells (ref).  \textit{Our \textbf{\textit{Our  previous findings} findings}}  \textit{Amplyfing (work in progress)} 

\textit{Our \textbf{\textit{Our  new findings} findings}}  \textit{Amplyfing (work in progress)} 

\textbf{JON, \textit{\textbf{JON,  WHERE DO YOU WANT TO PLACE THIS SUBCHAPTER?} SUBCHAPTER?}}  $\textrm{d}\theta = 2\pi /{T_1} \textrm{d}t + f_1(\theta) + F_1(\theta,\phi) \textrm{d}t + \sigma_1 \textrm{d} W^1_t $