this is for holding javascript data
Rosamaria Cannavo edited Introduction.tex
about 9 years ago
Commit id: 3ceda57c991390c7f8f6176043bcee6474ab72ac
deletions | additions
diff --git a/Introduction.tex b/Introduction.tex
index 3ec7507..fdc73a6 100644
--- a/Introduction.tex
+++ b/Introduction.tex
...
In this follow-up study we further analyze the dynamics of the two interacting oscillators by applying probabilistic inference to the whole signal allowing us to reconstruct the full phase dynamic of this interaction. Rather than relying on detected division times we use the measured area of the nucleus as a continuous variable to monitor cell cycle progression, as cell cycle area shows a consistent growth pattern between two divisions \cite{Fidorra1981}.
The analysis of the resulting model indicates that the biological system present several important features of resonating oscillators.
Moreover, this analysis allows us to make more specific predictions on distinct cell cycle events affecting the circadian clock, such the condensation of chromosomes starting from prophase during mitosis. We then test those prediction using further markers of cell cycle events.