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Kyunghwa Jeong edited figures/Fig_1/caption.tex
almost 9 years ago
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In 10 mM Ba\textsuperscript{2+}, currents were elicited by depolarizing step pulses in 10 mV increments from \textminus70 mV to +40 mV from a holding potential of \textminus90 mV.
(Right) I-V relationships of DmCa\textsubscript{v}3 and Ca\textsubscript{v}3.1.
Peak currents for each oocyte were normalized to the maximum current recorded.
Averaged percent amplitudes (mean $\pm$ s.e.m.) from oocytes expressing DmCa\textsubscript{v}3
($\circle$) (\circle) or Ca\textsubscript{v}3.1 ($\square$) are plotted against test potentials and fitted with Boltzmann equation.
{\bf(b)} (Left) Steady-state inactivation was measured during voltage steps to \textminus20 mV after 10 sec prepulse to potentials between \textminus100 mV and \textminus40 mV.
(Right) Voltage-dependent activation and steady-state inactivation curves of DmCa\textsubscript{v}3 channel ($\fullmoon$, $\newmoon$) and Ca\textsubscript{v}3.1 ($\square$, $\blacksquare$) were plotted and fitted with Boltzmann equation.
{\bf(c)} The activation time constant ($\tau$\textsubscript{act}) and inactivation time constant ($\tau$\textsubscript{inact}) of DmCa\textsubscript{v}3 ($\fullmoon$) and Ca\textsubscript{v}3.1 ($\square$) were obtained by fitting the current traces with double exponentials simultaneously.
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