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\subsection*{Statistical analysis}  Statistical analysis was performed using R (version 3.2.0)\cite{undefined} except data analysis of electrophysiological recordings (GraphPad, San Diego, CA, USA).  We used "car" and "userfriendlyscience" R packages.  If data is normally distributed, Welch's t-test was performed.  If data is not normally distributed, Kruskal-Wallis test followed by Dunn's multiple comparison test was performed.   
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