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\subsection*{Statistical analysis}  Statistical analysis was performed using R (version 3.2.0)\cite{R} except data analysis of electrophysiological recordings (GraphPad, San Diego, CA, USA).  Welch's t-test/Welch's one-way analysis of variance (ANOVA) for unequal varianced data  One-way analysis of variance (ANOVA)  Mann-Whitney U test  We used "car"\cite{car} and "userfriendlyscience"\cite{user} R packages.    
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