ROUGH DRAFT authorea.com/118696
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  • Merridown analysis

    Summary

    • The final predictive model for CIMT Max included SBP, Hba1c and Homocystein, as well as the interaction between SPB and Hba1c.

    • SBP, Hba1c and Homocystein are all affected by Statin use and the use of BP medication

    • SBP is affected by Hba1c and Homosystein

    • Apoliprotein A1 is a significant predictor of Hba1c

    • Apoliprotein A1 shares significant relationships with HDL and Statin use.

    Analysis of complete records/missing data

    Across all patient records, there were no complete records for data collected between 2008 and 2013. To investigate the missing data structure, an indicator matrix was constructed with the same dimension as the dataset. Each entry was coded as a 0 or 1, depending on whether an observation was recorded.

    Variable Obs_available percent.avail
    1 ID 1508.00 100.00
    2 year 1508.00 100.00
    3 alt 623.00 41.31
    4 ApoliA1 610.00 40.45
    5 ApoliB 609.00 40.38
    6 ast 622.00 41.25
    7 BG 628.00 41.64
    8 BMI 264.00 17.51
    9 Chol_lower 275.00 18.24
    10 CIMT_Max 1507.00 99.93
    11 CIMT_Mean 1508.00 100.00
    12 DBP 1343.00 89.06
    13 ECGInterpretation 282.00 18.70
    14 ExerciseECGInterpretation 236.00 15.65
    15 Ferritin 491.00 32.56
    16 FEV1 55.00 3.65
    17 Fob 472.00 31.30
    18 gamma_gt 623.00 41.31
    19 hb 645.00 42.77
    20 Hba1c 553.00 36.67
    21 hct 651.00 43.17
    22 HDL 224.00 14.85
    23 Homocys 543.00 36.01
    24 HR 8.00 0.53
    25 LDL 222.00 14.72
    26 Leucocytes 541.00 35.88
    27 METSWATTS 239.00 15.85
    28 MMSE 6.00 0.40
    29 Plaque 43.00 2.85
    30 psa 280.00 18.57
    31 QRS 8.00 0.53
    32 SBP 1343.00 89.06
    33 Serum_lipoA 6.00 0.40
    34 Sigma_Chol 453.00 30.04
    35 STChanges 238.00 15.78
    36 Triglyc 433.00 28.71
    37 TSH 483.00 32.03
    38 urate 627.00 41.58
    39 VE 12.00 0.80
    40 VO2MAX 36.00 2.39
    41 WCC 643.00 42.64
    42 Weight 292.00 19.36
    43 Age 1508.00 100.00
    44 BP 1508.00 100.00
    45 Statins 1508.00 100.00
    46 BT 1508.00 100.00
    47 crp_gt3 627.00 41.58
    48 VitaminB12_gt300 287.00 19.03
    49 VitaminD_combined 550.00 36.47
    50 egfr_gt90 665.00 44.10
    51 Gender 1497.00 99.27
    52 Height 1459.00 96.75
    53 Smoking 498.00 33.02
    54 Alcohol 359.00 23.81
    55 Exercise 403.00 26.72
    56 Dementia 413.00 27.39
    57 Dementia_Year 3.00 0.20
    58 Alzheimers 413.00 27.39
    59 Alzheimers_Year 2.00 0.13
    60 Hypertension 409.00 27.12
    61 Hypertension_Year 173.00 11.47
    62 HeartFailure 409.00 27.12
    63 HeartFailure_Year 6.00 0.40
    64 CVD 409.00 27.12
    65 CVD_Year 67.00 4.44
    66 OtherHeartproblems 409.00 27.12
    67