Aims
The flavonoid (2S)-5,7-dihydroxy-8-(3-methylbut-2-enyl)-2-phenyl-2,3-dihydrochromen-4-one (8P), extracted from the aerial parts and roots of the plant native in South America has antitirosinkinase activity.[1,2]
The objective of this study was the optimization of the labelling procedure of 8P with carbon-11 for its evaluation as potential GSK3 inhibitor for molecular imaging in Alzheimer's disease.