Fibrillogenesis of D76N and WT in presence of hydrophilic-hydrophobic interfaces. A, tapping mode AFM images of fibrils formed by D76N in the presence of graphite sheets under stirring conditions (I) or without agitation (II). B, time course of fibril formation by D76N under ultrasonication (light blue lines show replicate experiments) in contrast to the absence of fibrillogenesis by wild type(red line) under the same conditions. D76N fibril formation was accelerated in the presence of carbon nanotubes (greenlines), whereas wild type (dashedblack line) did not aggregate. C, fibrillogenesis of D76N (red triangles) and wild type2m(black triangles) carried out under stirring conditions at 37°C in the presence of a Teflon-water interface with 6M human elastin. a.u., arbitrary units.