3.1. AS-IV increases the cell viability of influenza-infected A549 cells but has no inhibitory effect on the influenza virus infection
Fig. 1A shows the chemical structure of AS-IV. Fig. 1B-C shows the toxicity of A549 cells treated with AS-IV for 72h. The results showed that AS-IV had no obvious toxicity to cells when the concentration reached 125µM, but when the concentration reached 250µM, AS-IV formed many drug crystals, and the cell viability was significantly decreased (P <0.01). Therefore, concentrations below 125µM were used for subsequent experiments.