4. Conclusion
In summary, the study demonstrates the protective effects of DACA
against MPTP-induced motor dysfunction, neurological deficit, and
neurodegeneration in a manner consistent. Additionally, DACA exhibits
antioxidant properties and plays a crucial role in maintaining
mitochondrial health and regulating mitophagy through Nrf2 activation
(Fig. 1). These findings significantly contribute to our understanding
of the intricate relationship between Nrf2 and Parkinson’s disease (PD).
Consequently, DACA holds great promise as a potential anti-PD drug for
further therapeutic interventions aimed at preventing PD occurrence and
progression. However, it is imperative to conduct future investigations
to explore other potential protective effects of DACA as well as its
multi-target mechanism of action.