Family History Tumor Patient Characteristics
Two or more neoplasia in family members before the age of 18 (including index case). Parents or siblings with cancer before age 45 Two or more 1st or 2nd-degree relatives degree relatives in the same family branch diagnosed with cancer before the age of 45. Consanguinity of the patient’s parents 1. Diagnosis of a type of tumor frequently associated with cancer predisposition syndromes 2. Finding a previous mutation in the tumor analysis suggesting a germline predisposition syndrome 3. Patient with 2 or more tumors (bilateral, multifocal, metachronous, or secondary tumor) 1. Phenotype compatible with a cancer predisposition syndrome 2.Patients with high toxicity to cancer treatment (toxicity not expected with the type, degree, or duration of the treatment received)