Patient selection
We scheduled specific appointments with families to collect comprehensive information about the family’s cancer history, any available molecular tumor data, and physical examination. If they met any criteria outlined in Table 1, we conducted genetic testing on the patient and their parents. Out of 50 patients, 44 (88%) met at least one criterion and underwent genetic testing, while the remaining 6 patients (12%) were excluded from the study. Results and workflow are shown in Fig.1.