Figure 1. Workflow and results of selected patients.
Of the patients, 47,7% met only one criterion, 40,9% met two criteria, 9,1% met three criteria, and 2,3% met four criteria. 16 patients were selected by family history (32%), 31 patients (50%) were selected by tumor type (24 by tumor diagnosis and 7 by the presence of a somatic variant detected in the tumor). 14 patients (28%) met the criteria for a compatible phenotype, and 11 patients (22%) due to experiencing high toxicity during treatment.
The patients selected by mutations present in the tumor were:
”Pre-data” and ”post-data” information were compared. Interestingly 24% of patients did not meet any criteria on the “pre-data” evaluation (at diagnosis), but did meet at least one criterion on the specific appointment for familial cancer (post-data) (Figure2).