INTRODUCTION
Sweet’s Syndrome (SS), also described as acute neutrophilic dermatosis is a dermatological condition characterized by red, raised and painful skin lesions often associated with fever and systemic symptoms1. SS is usually described in association with various systemic illnesses, including malignancy2. SS associated with acute myeloid leukemia (AML) is described, however published literature with regards to childhood AML is sparse. It is very important to suspect and diagnose Sweet’s syndrome early, to differentiate it from other common skin manifestation of myeloid malignancy like leukemia cutis, chloroma or infective skin lesions. We describe the management of a child presenting with Sweet’s syndrome during relapse of the AML and intend to discuss the clinical insights, management aspects and concisely review the published literature.