INTRODUCTION
Sweet’s Syndrome (SS), also described as acute neutrophilic dermatosis
is a dermatological condition characterized by red, raised and painful
skin lesions often associated with fever and systemic
symptoms1. SS is usually described in association with
various systemic illnesses, including malignancy2. SS
associated with acute myeloid leukemia (AML) is described, however
published literature with regards to childhood AML is sparse. It is very
important to suspect and diagnose Sweet’s syndrome early, to
differentiate it from other common skin manifestation of myeloid
malignancy like leukemia cutis, chloroma or infective skin lesions. We
describe the management of a child presenting with Sweet’s syndrome
during relapse of the AML and intend to discuss the clinical insights,
management aspects and concisely review the published literature.