3.1 Iron overload
Serum ferritin was available in all 45 patients. T2*MRI was performed in all except one patient due to the need for sedation. The mean serum ferritin was 581 ng/ml (range: 32-2115). Iron overload (serum ferritin >1000 ng/ml) was observed in 5 (11.1%) patients. CRP levels were <10 ng/ml in all. The mean LIC was 2.7 mg/g (range: 0.6-12.7). The LIC was elevated (>2 mg/g) in 20 (45.4%) patients; 18 (41%) had mild, and 2 (4.5%) patients had a moderate grade of hepatic iron overload. The mean MIC was 0.6 mg/g (range: 0-1.6). Merely 2 (4.5%) patients had an elevated MIC, both with a mild elevation. The two patients with the cardiac iron overload included a patient with high-risk ALL and another with AML. An echocardiogram was performed in both patients with cardiac iron overload. The ALL survivor had grade 2 diastolic dysfunction, and the other had a normal function.