Fejzo
2016 [33]
|
Cohort study
|
USA
|
The Hyperemesis Education and Research Foundation
|
2007-2014
|
Women who did not have a history of HG
|
NR
|
1070/771
|
Yes
|
ÖZDEMİRC 2014 [34] |
Cohort study |
Turkey |
NR |
2006-2011 |
Chlorpromazine |
NR |
100/85 |
NR |
Colvin
2013 [35]
|
Cohort study
|
Australia
|
NR
|
2002–2005
|
Non-ondansetron
|
NR
|
251/96447
|
Yes
|
Berard
2019 [36]
|
Cohort study
|
Canada
|
The Quebec Pregnancy Cohort
|
1998-2015
|
Unexposed
|
The first trimester of
pregnancy
|
31/224845
|
Yes
|
Asker 2005 [37] |
Cohort study |
Sweden |
The Swedish Medical Birth
Registry |
1995-2002 |
Unexposed |
First to
third
trimester
|
29804/665572 |
Yes |
Dormuth 2021 [38]
|
Cohort study
|
Canada\USA\
UK
|
Five Canadian provinces, the IBM Market Scan Research Databases from
the US, and UK CPRD,
|
2002-2016
|
Unexposed
|
The first 84 days of gestation
|
185086/3927936
|
Yes
|
Lemon
2020 [39]
|
Cohort study
|
USA
|
Magee–Womens Hospital of the University of Pittsburgh Medical Center
(UPMC)
|
2006-2014
|
No ondansetron
|
The first trimester
|
3733/29944
|
Yes
|
Einarson
2004 [40]
|
Cohort study
|
Canada
|
Teratogen Information Services (TIS)
|
NR
|
Other antiemetics/
Non-teratogen
|
NR
|
176/176/176
|
Yes
|
Huybrechts 2020 [41] |
Cohort study |
USA |
The Nationwide Medicaid
Analytic eXtract (MAX) |
2000-2014 |
Unexposed |
NR |
23877/1856717 |
Yes |
Suarez
2020 [42]
|
Cohort study
|
USA
|
The University of North Carolina (UNC) Health Care system
|
2014-2017
|
Comparators
|
NR
|
1742/935
|
Yes
|
Pasternak 2013 [43] |
Cohort study |
Denmark |
The Medical Birth
Registry and the National Patient Register in Denmark |
2004-2011 |
Unexposed |
The first trimester |
1849/7396 |
Yes |
Werler
2014 [44]
|
Case-control study
|
USA
|
NR
|
2007-2011
|
Controls
|
NR
|
646/2037
|
No
|
Zambelli-Weiner
2019 [45]
|
Case-control study
|
USA
|
US administrative health care database, the Truven Health Market Scan
Commercial Database
|
2000-2014
|
Unexposed During Pregnancy
|
The first trimester
|
76330/787753
|
Yes
|
Sakran
2021 [46]
|
Case-control study
|
Israeli
|
The Israeli Teratology Information Service
|
2010-2014
|
Metoclopramide/NTE
|
NR
|
195/888
|
NR
|
Danielsson
2014 [47]
|
Case–control study
|
Sweden
|
The Swedish Medical
Birth Register combined with the Swedish Register of Prescribed
Drugs
|
1998-2012
|
Meclozine
|
10-12w
|
1349/1500085
|
NR
|
Parker
2018 [48]
|
Case–control study
|
USA
|
The National Birth Defects Prevention Study/the Slone Birth Defects
Study
|
2005-2011/
1997-2014
|
RxAE/No Treatment
|
NR
|
253/6498;375/5498
|
Yes
|
Couse
2020 [49]
|
Case report study
|
USA
|
NR
|
NR
|
NR
|
NR
|
NR
|
No
|
Lemon
2016 [50]
|
Case report study
|
USA
|
NR
|
NR
|
NR
|
NR
|
NR
|
Yes
|
Ferreira,2012 [51] |
Case series study |
USA |
NR |
2002-2011 |
NR |
NR |
14 |
NR |