Random-Pattern Skin Flap Model
The back hair was removed, and all rats were intraperitoneally
anesthetized with 40 mg/kg of 2% (w/v) sodium pentobarbital. By cutting
the skin along a specified line (3cm × 9cm), random skin flaps were
created. The skin was cut along the design line, and the skin flap
underwent entire separation from the deep fascia. The bilateral sacral
arteries were cut off and finally sutured in situ intermittently with
4-0 sutures. Each flap had three equal zones: zone I (proximal), zone II
(intermediate), and zone III (distal) (Figure 1 ).