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\begin{document}

\title{Perceptions, healthcare messaging and its impact on COVID vaccine uptake
in pregnancy : A cross-sectional survey}



\author[1]{Sonika Sethi}%
\author[2]{Amy Thompson}%
\author[2]{Ehsaan Qureshi}%
\author[3]{Anna Stone}%
\author[2]{James Bateman}%
\author[2]{Supratik Basu}%
\author[2]{Matthew Brookes}%
\author[2]{Francina Schreuder}%
\affil[1]{Sandwell and West Birmingham Hospitals NHS Trust}%
\affil[2]{Royal Wolverhampton Hospitals NHS Trust}%
\affil[3]{Thornley Street Medical Centre}%


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  \date{May 22, 2024}


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\begin{abstract}
Objective: To gain in-depth insights into factors affecting COVID-19
vaccine acceptance in pregnant women. This demographic has lower rates
of COVID vaccination despite being disproportionally negatively affected
by COVID. Design: A single centre cross-sectional online survey
distributed 13th August 2021 to 21st September 2021 on local networks.
Setting: Online Population: Pregnant population in a large District
General Hospital in the West Midlands, UK. Main Outcome Measures: i)
demographic and baseline data ii) awareness of information sources; iii)
opinions on COVID and vaccination, iv) vaccination decisions. Results:
92 total eligible responses were quantitatively and qualitatively
analysed. 60.9\% (n=56) had declined, or would decline, a COVID-19
vaccination. Those who had a previous negative pregnancy experience were
significantly more likely to accept a COVID-19 vaccination (OR 3.9;
p\textless{}0.05, 95\% CI 1.32-11.52). Over half (53.2\%) of
participants either agreed or strongly agreed that discussion with a
healthcare professional was important in decision making on vaccination
. GPs were the least supportive of the vaccination (62.5\%) compared to
midwives (78.8\%) and obstetric consultants (81.8\%). The most common
reason for declining the vaccine were perceived risks to the fetus; this
was also frequently reported in the qualitative analysis. Other
qualitative themes included; distrust of recommendations, conflict of
information and uncertainty. Conclusions: There is a need for consistent
health professional messaging around vaccine uptake in pregnancy and the
use of appropriate evidence based information, particularly focusing on
its safety and impact on fetus. There is a need to nurture a
collaborative approach and informed decision making.%
\end{abstract}%



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\verb`Perceptions, healthcare messaging and its impact on COVID vaccine uptake in pregnancy - A cross-sectional survey.docx`  available at \url{https://authorea.com/users/740046/articles/713225-perceptions-healthcare-messaging-and-its-impact-on-covid-vaccine-uptake-in-pregnancy-a-cross-sectional-survey}

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