Literature search
This search was restricted only to articles published in English and
Chinese language. We searched for publications on the PubMed,
Embase,
Cochrane Central Register of
Controlled Trials, Clinical trials, CNKI, Wanfang Data, VIP, CBM up to
August 2021. We did keyword, and
Medical Subject Heading
(MeSH) searches for our theme, and
MeSH terms, keywords, and their synonyms related to ”Fingolimod
hydrochloride” and ”Cerebrovascular Disorders.” A flowchart of the
search strategy is shown in Fig. 1. One of us used a standardized form
of data extraction to extract data; another person checked it, and
revisited the data that did not match, and resolved the differences
through discussion and consensus.