Conclusion
Our results demonstrated that Canadian PCV3 strains submitted to
diagnostic laboratories and sequenced in this study were not diverse.
All of the Canadian strains classified into PCV3a and segregated into
different clusters with strains from North America, South America, Asia
and Europe. Amino acid polymorphisms found in this study indicated the
importance of these differences for understanding the evolutions of
these strains. This is the first phylogenetic analysis of PCV3 strains
among different provinces in Canada. The new PCV3 sequences will allow
further investigations to explore the evolutions of PCV3 and future
studies are required to better determine the polymorphisms in cap
proteins could be associated with differences in the pathogenicity or
antigenicity of PCV3 strains.