3.4 Thermal stability
According to the criteria whether HA titer would decrease two
units after incubated at 56°C for 5
and 30 min, the AIVs can be divided into three types:
thermal instability (HA titer
decreased two units in 5 min), thermal stability (HA titer decreased two
units in 30 min) and moderate thermal stability (in between) (He et al.,
2018). The results (Figure 3A)
showed that the HA titers of both
strains didn’t decrease within 30
min, suggesting they were thermal
stable viruses. We could also see that the virus titers of both strains
changed to 0 within 15 min (Figure 3B), indicating low infectivity of
them. To summarize, incubation of the viruses at 56°C didn’t influence
their HA activity too much, but infectivity was significantly reduced.