Case 2: SARS-CoV-2 attack on a healthy person with pre-existing
conditions.
If SARS-CoV-2 infects a person who has a pre-existing condition like
heart disease or Asthma, it will make the person sicker and affect them
more than if they did not have a pre-existing condition. Quantum
Perturbation Theory describes that in this case, the total effect of
COVID-19 on the person attacked by the virus will be the sum of
unperturbed energy and the first-order correction of energy. Thus,
mathematically
Strength of Covid-19 attack on a person with pre-existing diseaseE = En(0) +
En(1)
E = <
Ψn(0) │H0│Ψn(0)> + < Ψn(0)│H
p│Ψn(0) > / <
Ψn(0)│Ψn(0)> (13)
Similarly, if a person has two chronic conditions and is infected with
coronavirus, the viral infectivity with the two pre-existing diseases
will be,
E = En(0) +
En(1) +
En(2)
Which gives,
E = <
Ψn(0) │H0│Ψn(0)> + < Ψn(0)│H
p│Ψn(0) > / <
Ψn(0)│Ψn(0)>
+ ∑ {│<
Ψn(0)│H
p│Ψj(0)>│2 / (
Ej(0) –
En(0) )} (14)
Thus, the existence of any number of pre-existing diseases will increase
the effect of COVID-19 infection and the extra risk is proportional to
the order of perturbation.
An important point worth noting here is the fact that every higher-order
perturbation contributes less energy than the lower-order perturbation.
Each additional disease is represented by a higher order of
perturbation. This results in a significant outcome that, if an
individual is affected by the COVID-19 and has one pre-existing disease,
then the effect is represented mathematically by the addition of
first-order correction to the energy. Similarly, if another person has
two existing diseases, then the effect of COVID-19 will be increased by
the sum of first-order energy correction and second-order energy
correction. Since second-order energy is less than the first order that
means doubling the pre-existing disease in a person will not double the
COVID-19 effect but the effect on the person will be less than double.
This could be most probably attributed to the fact that in the presence
of two pre-existing diseases as compared to one when coronavirus attacks
then the immunity system of the person will be more active and will
fight stronger. As a result, the COVID-19 effect will be less than
double. The effect of COVID-19 on a healthy person and on patients with
one or more pre-existing chronic diseases is given in Figure 3.