Case 2: SARS-CoV-2 attack on a healthy person with pre-existing conditions.
If SARS-CoV-2 infects a person who has a pre-existing condition like heart disease or Asthma, it will make the person sicker and affect them more than if they did not have a pre-existing condition. Quantum Perturbation Theory describes that in this case, the total effect of COVID-19 on the person attacked by the virus will be the sum of unperturbed energy and the first-order correction of energy. Thus, mathematically
Strength of Covid-19 attack on a person with pre-existing diseaseE = En(0) + En(1)
E = < Ψn(0)H0│Ψn(0)> + < Ψn(0)│H p│Ψn(0) > / < Ψn(0)│Ψn(0)> (13)
Similarly, if a person has two chronic conditions and is infected with coronavirus, the viral infectivity with the two pre-existing diseases will be,
E = En(0) + En(1) + En(2)
Which gives,
E = < Ψn(0)H0│Ψn(0)> + < Ψn(0)│H p│Ψn(0) > / < Ψn(0)│Ψn(0)>
+{│< Ψn(0)│H p│Ψj(0)>│2 / ( Ej(0) – En(0) )} (14)
Thus, the existence of any number of pre-existing diseases will increase the effect of COVID-19 infection and the extra risk is proportional to the order of perturbation.
An important point worth noting here is the fact that every higher-order perturbation contributes less energy than the lower-order perturbation. Each additional disease is represented by a higher order of perturbation. This results in a significant outcome that, if an individual is affected by the COVID-19 and has one pre-existing disease, then the effect is represented mathematically by the addition of first-order correction to the energy. Similarly, if another person has two existing diseases, then the effect of COVID-19 will be increased by the sum of first-order energy correction and second-order energy correction. Since second-order energy is less than the first order that means doubling the pre-existing disease in a person will not double the COVID-19 effect but the effect on the person will be less than double. This could be most probably attributed to the fact that in the presence of two pre-existing diseases as compared to one when coronavirus attacks then the immunity system of the person will be more active and will fight stronger. As a result, the COVID-19 effect will be less than double. The effect of COVID-19 on a healthy person and on patients with one or more pre-existing chronic diseases is given in Figure 3.