Recurrence rate:
Figure 1 is a forest plot of the percent of recurrence of any atrial fibrillation, atrial tachycardia or atrial flutter after the blanking period recorded using a Holter monitor (13) or an implanted monitor (11) that patients had on them throughout the trial period. Subgroup analyses was deemed unnecessary due to low heterogeneity was and limited number of studies included.
Total number of participants with recurrence of symptoms after the blanking period was 76 out of 261 (29%) for the Cryoablation group and 134 out of 260 (50%) for the AAD group.
The metaanalysis generated a pooled RR for overall recurrence of symptoms of 0.60 for CA Versus AAD (95% CI 0.49, 0.74, P < 0.00001, I2=0%), using the fixed effect model, out of the two included studies (n=521)