Antifungal use
Use of antifungals in PHO units before and after PHIG intervention is shown in Table 5 . Overall, 47.4% of patients before and 46.9% after the intervention received at least one antifungal (p =0.893). Almost all patients treated in the BMT unit were receiving at least one antifungal at the time of data collection. Almost two thirds of children treated in units located in general hospitals were receiving at least one antifungal compared to approximately one fourth of patients treated in units located in pediatric hospitals. In unit 6, antifungal use significantly increased after intervention (p =0.044). Overall, use of at least one antifungal was significantly more common in PHO units located in general versus pediatric hospitals before the intervention (66% compared to 40.9%,p =0.001) and remained so after the intervention (73% compared to 36.2%, p =0.001).