Statistical analysis
The prevalence of tocilizumab
off-label use was calculated by the number of off-label prescribed
patients divided by the total number of
tocilizumab used patients.
Additionally, the proportion of each off-label indication among the
total off-label prescriptions was also analyzed. Finally,
we compared how different
professional titles affect off-label use of tocilizumab prescribing with
analysis of logistic regression.