Conclusion
To conclude, our data imply that identifying and validating indicators for predicting COVID-19 disease progress to improve health outcomes is crucial. Age, immunological response, comorbidities, radiographic abnormalities, signs of organ dysfunction, and laboratory markers could predict poor outcomes individually or collectively. Because SARS-CoV-2 has a tropism for various tissues, such as the brain, endothelium, heart, kidney, liver, and respiratory system, predicting the COVID-19 severity is much more challenging. It is critical to identify characteristics that predict COVID-19 problems to guide clinical management, improve patient outcomes, and allocate limited resources.