Blood Immunosuppressant Concentration
Tacrolimus levelTwo RCTs reported tacrolimus blood levels and the mean and standard
differences were extracted from three(21 , 23 , 25 ,27 ). A total of 254 patients participated in these two studies
and the fixed-effects model was used in this analysis owing to the no
heterogeneity (I²=0%, p=0.38). Results of this meta-analysis found no
significant group differences on the Tacrolimus level MD = 0.16 (95%
CI: -0.21 to 0.52, p = 0.39)(Figure 6). While other (27 ) did
not provide analyzable data or median and mean, thus precluding the
possibility for combining these statistics with other data. Henriksson
et al. (27 ) found there was no significant difference in
tacrolimus concentration between the 2 groups over the 1-year
follow-up period.