Conclusion
In conclusion, this study provides the data on iron nutritional status
and thyroid hormones of pregnant second-trimester women in Pingguo
County. During the second trimester of pregnancy, ID may result in lower
FT4 and FT3 and higher TSH, and these findings are consistent with the
earlier reports. Indeed, SF is positively correlated with FT3 and FT4
levels, and negatively correlated with TSH levels. Hb may also play a
certain role in affecting the thyroid function. Although the specific
mechanism is still unclear, the correlation between iron nutrition and
thyroid hormone should not be underestimated. Involving two common
endocrine diseases in pregnancy, the relationship between ID and thyroid
hormone, the molecular mechanisms involved, and the disease consequences
deserve further investigation. From the perspective of maintaining
maternal health and offspring’s health, we recommend that ID should be
estimated and treated to prevent thyroid dysfunction during the second
trimester of pregnancy or even earlier. In addition, it also provides a
new idea and reference for improving the quality of life of pregnant
women and their offspring.