METHODS
Demographic and clinical information was abstracted. We performed ELISAs to identify and quantify HAstV-1 and HAstV-VA1 specific antibodies in 9 polyvalent IVIG lots. In addition, we performed neutralization as described elsewhere. 18 (Supplemental methods) The study was approved by St Jude’s Institutional Review Board. Consent from parents of Patient 2 was waived and verbal consent from parents of Patient 1 was obtained.