Acknowledgements
Author Contributions: H.M ,
Y.M and S.M contributed to the conception and design of the study. S.M,
H.R, P.Y, H.X, H.W, D.C, J.T, T.G and J.L were responsible for data
acquisition, analysis, and interpretation. H.M, S.M, H.R, P.Y
contributed to the discussion and reviewed/edited the manuscript, and
all authors reviewed the manuscript.
Funding: This research was supported by
Science
and Technology Bureau of Chongqing(STBC), China, project No:
cstc2019jscx-msxmX0267, but STBC did
not participate in the design, implementation, data collection, analysis
and article writing process of the study.
Competing
interests: The authors declare no
competing interests.
Trial registration: ChiCTR2000029017. Registered on
11/01/2020-Prospective registration, http://www.chictr.org.cn/