Acknowledgements
Author Contributions: H.M , Y.M and S.M contributed to the conception and design of the study. S.M, H.R, P.Y, H.X, H.W, D.C, J.T, T.G and J.L were responsible for data acquisition, analysis, and interpretation. H.M, S.M, H.R, P.Y contributed to the discussion and reviewed/edited the manuscript, and all authors reviewed the manuscript.
Funding: This research was supported by Science and Technology Bureau of Chongqing(STBC), China, project No: cstc2019jscx-msxmX0267, but STBC did not participate in the design, implementation, data collection, analysis and article writing process of the study.
Competing interests: The authors declare no competing interests.
Trial registration: ChiCTR2000029017. Registered on 11/01/2020-Prospective registration, http://www.chictr.org.cn/