Systematic review
The summarized result for all studies in China were shown in Figure 3A.
In general, the top two diseases based on the weighted average ratio
were genital inflammation and menstrual disorder across 33 studies. The
random pooled ES was 33·7% (95% CI 22·7% to 45·5%) for genital
inflammation, and 23·0% (95% CI 15·9% to 31·0%) for menstrual
disorders (Figure S4A and S4B). Overall heterogeneity was significant
among studies evaluating genital inflammation and menstrual disorder
with I2 (test for heterogeneity) being 99·80% and
99·62% respectively, indicating substantial heterogeneity in different
studies. In the stratified analyses by clinic setting, we observed a
different pattern of PAG issues between outpatients and inpatients
studies. For inpatient studies, the most frequent diseases were genital
tumor, menstrual disorder and genital inflammation (Figure 3B). For
outpatient studies, genital inflammation is the mainly observed among
all gynecological diseases (48·8%), followed by menstrual disorders
(25·2%), other endocrine problems (7·2%), early puberty (5·6%) and
genital trauma (4·7%). The proportion of other diseases were less than
4% (Figure 3C).