PAG patterns overall and by age groups
In terms of PAG problems, more than half (57·0%) of adolescents
presented with gynecologic inflammation symptoms at the first clinical
visit (Table 2). Diagnoses related to early puberty and consultation of
growth and development accounted for 18·2% and 10·2% of first visits,
respectively. The proportion of other conditions such as gynecological
examination, menstrual disorder, other endocrine problems, genital
trauma, masturbation syndrome, anomalies of the genital tract, and
genital tumor ranged from 0·5% to 5·6%. The patterns of PAG problems
were different across different age groups. Among pediatric patients
under 6 years of age, genital inflammation was the most common
presentation (78·5%), followed by early puberty, and gynecological
examination, accounting for 11·4% and 5·2% of the cases, respectively.
Among patients aged 7 to 9 years, the top three diagnoses were genital
inflammation (43·4%), early puberty (39·6%), and consultation of
growth and development (10·4%). As for the patients aged 10 to 18
years, 34·9% of their first PAG clinic visits were for consultation of
growth and development; the remaining cases were genital
inflammation (21·4%), menstrual disorder (20·7%), gynecological
examination (9·4%), early puberty (7·2%) and other endocrine problems
(4·1%). The distribution of PAG problems across different age groups
with an interval of two years is shown in Figure S1. The age range for
which genital inflammation represented the highest proportion of cases
was 0-8 years, while the percentage of the disease dropped below 50%
for patients aged 8 and above. Other diseases with significant age peaks
included early puberty (ages 6-10), consultation of growth and
development (ages 10-14), and menstrual disorder (ages 12-18).